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The Organic Pharmacy Gene Expression Lifting Serum




Size: 40ml

Inspired by the science of how our genes can affect our ageing made possible by advances in gene mapping and how we can protect our cells by using and taking the right ingredients.

Gene Expression Lifting Serum is the culmination of years of research and the latest innovation in a serum that helps dramatically improve the appearance of the seven signs of ageing.


  • 10 active ingredients combine in a serum that changes the way your genes express ageing and restores skin to its youthful state
  • Can be mixed with your moisturiser to increase its potency and results
  • Replenishes lost moisture and forms a barrier on the skin to prevent further loss and improve texture
  • Pigmentation, wrinkles and loss of elasticity are reduced, skin feels both firmer and more toned after continued use

10 Actives – 7 Actions

  • Grape Stem Cell – Protect skin from the effects of UV aging
  • Retinol/Glucosamine Cosmeceutical – Pigmentation/Wrinkles
  • Vegetable Peptide Gene cosmeceutical – Firmness
  • Hibiscus Growth Factor – Skin Texture/Elasticity
  • Flax seed GAG – Remodelling
  • Sodium Hyaluronate Algae Cosmeceutical – Plumping
  • Sea Algae Marine Active – Hydration


Apply twice a day morning and night after moisturising.

The Proof

Clinical studies were carried out by an independent institute specialising in dermal 3D imaging and the results proved that it works.

After 2 weeks:

  • 92% agree skin looks more radiant
  • 86% agree dark spots are diminished
  • 88% agree skin is plumper and smoother
  • 82% agree fine lines and wrinkles appear diminished
  • 100% would buy and recommend to a friend
  • 85% agree skin appears more elastic

New Gene Expression Lifting Serum

The modulation of gene expression as a new skin anti-aging strategy has been looked at for several years however it wasn’t until I spent time with the geneticists at Imperial College that I fully understood that we can actually change the way our genes express ageing through nutrition, stress reduction, less toxicity and the use of powerful topical actives.

Recent advances in the mapping of the human genome have given us the opportunity to explore how we age and the role of gene expression in ageing and how supplementation and nutrients interact with genes expression.

If we look at ageing as long term damage to cells and tissue at a molecular level, the rate of ageing depends on internal and external factors that influence the balance between repair of damage and tissue longevity. It is now accepted that lifestyle factors can accelerate or decelerate this ageing process:


By understanding genetic markers and the environment that accelerates ageing my aim was to formulate a super serum that addressed both genetic and environmental ageing triggers.

Gene Expression Lifting Serum is the result of combining the optimal actives (it has 10 actives in total) to work in synergy to address all the ageing skin issues:

Skin texture, uneven skin tone, surface dullness, appearance of enlarged pores, loss of elasticity, dehydration/dryness, Appearance of fine lines and wrinkles, sagging skin and premature ageing. A combinations of plant based bio technological extracts, antioxidants, vitamins, remodelling, stem cells, growth factors and lifting herbs and 3 different sized Hyaluronic acid molecules(low, medium and high molecular weight) to hydrate and plump the skin. These 10 actives Combine to deliver with 7 actions in a serum to change the way our genes express ageing and restore our skin to its youthful state.


ACTIVES: Sodium Hyaluronate, Sea Algae, Gluconolactone

ACTION: Hydration, Pluming, Elasticity, Wrinkle Reduction

Sodium Hyaluronate and Sea Algae extract derived from university based biomedical engineering with incredible tissue affinity and adhesivity originally designed for the promotion of wound healing. The polysaccharide biopolymers from specially selected Chondrus crispus rich in hyaluronic acid create bundles that deliver bolus and adsorbed water for immediate and sustained hydration.

Also rich in Gluconolactone an important molecule found in the bodies of many mammals. Topically, it’s molecules are naturally attracted to water. When the ingredient is applied to the skin, these “water hungry” molecules pull moisture out of the air and allow it to be absorbed by the skin. By drawing water droplets from the air in this way, gluconolactone helps to soften and soothe dry skin and replenish lost moisture. In addition, gluconolactone forms a barrier on the skin, preventing moisture already present in the tissue from evaporating. A 2004 study published in the journal of “Dermatologic Surgery” found that gluconolactone may function as an antioxidant, protecting the skin from premature aging by neutralizing free radicals. The study also suggested that the ingredient has sun-protective properties and can help prevent damage to the skin that is caused by exposure to harsh ultraviolet radiation. In fact, the results of the study showed that gluconolactone boosts UV protection by as much as 50 percent.


ACTIVES: Flax Seed Extract and Birch Extract

ACTION: Resculpting / Resculpting / Remodeling / Antisagging

Not the oil extracts but the mucilage of the fax seeds and juice of the birch bark and leaf provide water soluble extracts that work in synergy to increase GAG synthesis, protect collagen from degradation and plump the skin through their high capacity to absorb water. The result is a remodeling action along the jaw line, increased skin hydration and lifting and remodeling of the contours of the face. A study with 24 volunteers aged 45-61 showed after 42 days – 75% had firmer skin, 92% visibly reduced lines, 67% plumper skin.


ACTIVES: Encapsulated and stabilised Nature Identical Retinol

ACTION: Visibly Smooth Wrinkles, Improve Skin Texture, Reduce Pores, Reduce the Signs of Pigmentation, Even out Skin Tone

Discovered 81 years ago by Nobel winning Swiss chemist Paul Karrer, retinol is still the most powerful anti-ageing ingredient on the market. All retinoids are derivatives of vitamin A, one of the body’s key nutrients. The problem for many years is to make it stable as it was prone to degeneration. Scientists then developed retinoic acid which later became Retin A which was FDA-approved in 1971 as a prescription-strength treatment for acne, but dermatologists noticed almost immediately that a patients began reporting a reduction in fine lines and hyperpigmentation. The issue however was the irritation, redness and dryness. It was also sensitive to light which meant it could only be used at night and it made the skin very sensitive. Retinol however is milder than retinoic acid and after decades of research it is now stable and able to remain in skin care without breaking down. When applied to the skin it is not active. It becomes active when it reaches the cells and is converted to retinoic acid by the cells. That means no irritation, no redness, no sun sensitivity or peeling but all the benefits: visibly smoothed out wrinkles, no breakouts, improved skin texture and tightened of pores

Reduced brown spots and a luminous glow.


ACTIVES: Hibiscus Abelmoschus Seed Extract – GROWTH FACTOR

ACTION: Collagen protector and Synthesis. Imporve skin texture, elasticity and thickness

An amino acid rich extract of hibiscus showed protective action towards Fibroblast Growth Factor 2 (FGF-2). In skin heparin, heparan sulphate and heparan sulphate proteoglycans control the storage and release of growth factors and protect them from early degradation. Hibiscus Abelmishus Extract can maintiain the FGF2 content of the skin by mimicking the protective effect of heparan sulphate proteoglycans. By preventing the natural degradation of FGF-2, Hibiscus Abelmoschus seed extract maintains the bioavailability of this growth factor for its target cells, i.e. skin fibroblasts. A study showed that the protected FGF-2 could stimulate the synthesis of sulphated GAGs, the natural protective molecules for FGF-2, and collagen synthesis thus providing a double protection. The result rejuvenated skin texture and density, improving the appearance of aging skin to resemble much younger skin in a matter of weeks.


ACTIVES: Vegetable Derived Peptide Trifluo tripeptide – 2

ACTION: Peptide that remodels and lifts sagging skin

A high tech biomimetic peptide derived from vegetable source acts by modulating progerin. The molecule Elafin is a protein encoded by the P13 gene which encodes an elastase- specific protease inhibitor.

Progerin is a protein associated with normal and abnormal ageing. In a genetic disorder called Hutchinson Gilford Progeria syndrome where the organs age at a vastly accelerated speed, the expression and accumulation of progerin was caused by a mutation in the Lamin A gene. A study carried out by the Univercity of Boston  demonstrated that exposure to UVA and UVB rays resulted in the release of oxygen species (free radicals) that caused alternative splicing of the LaminA gene pre-mRNA which causes the release of progerin. This brings us a little closer to understanding the mechanisms of photoaging.

This peptide acts by controlling the release of Progerin resulting in a complete remodelling effect and a reduction in the appearance of wrinkles and sagging skin.


ACTIVE: Grape Stem Cell Extract

ACTION: Protect Skin Stem Cells against UV-induced Aging

UV radiation is responsible for 80% of face aging. Despite the use of sun filters, toxins and oxidants are generated by UV in the skin. This affects the most sensitive cells such as the epidermal stem cells which are rare and essential. Thus, their protection against UV stress is of great importance.

A rare grape cultivar of Gamay was selected. Stem cells from this cultivar were obtained with special extraction technology and were then incorporated in a water-soluble powder. These grape stem cells contain special epigenetic factors and metabolites which are able to protect human skin stem cells against UV radiation.

Using a novel Progenitor Cell Targeting technology, this Grape Stem cell was shown to:

•help the skin stem cells to maintain their stem cell characteristics

•protect these precious cells against UV-induced stress. A clinical study showed the it also to increase the tolerance of the skin to UV

It can thus protect both the skin and the epidermal stem cells against the stresses induced by UV, the main aging factor.

•Protects skin stem cells against UV stress

•Increases the skin’s UV tolerance

•Fights photo-aging

•For a vital and healthy-looking skin


ACTIVE : Glucosamine & Aloe

ACTION: Anti-inflammatory and reduce wrinkles and reduce pigmentation/uneven skin tone

Both glucosamine and its derivative N-acetyl glucosamine are amino-monosaccharides that serve key biochemical functions on their own and as substrate precursors for the biosynthesis of polymers such as glycosaminoglycans (e.g., Hyaluronic acid) and for the production of proteoglycans. Glucosamine compounds have been reported to have several beneficial effects on the skin or skin cells. Because of its stimulation of hyaluronic acid synthesis, glucosamine has been shown to accelerate wound healing, improve skin hydration, and decrease wrinkles. In addition, as an inhibitor of tyrosinase activation, it inhibits melanin production and is useful in treatment of disorders of hyperpigmentation. Mechanistically, glucosamine also has anti-inflammatory effects.



Aloe (Aloe Barbadensis)*, Aqua (Water) , Glycerin (vegetable)*, Titanium Dioxide , Mica, Benzyl Alcohol, Sodium Hyaluronate, Isomalt, Silica, Carbomer, Hibiscus (Hibiscus Sabdariffa), Linseed (Linum Usitatissmum), Sodium Hydroxide, Xanthan Gum, Glucosamine Hydrochloride, Lecithin, Iron Oxides, Biosaccharide Gum-1, Sorbic Acid, Grapeseed Extract (Vitis Vinifera), Phospholipids*, Chondrus Crispus Extract, Isomalt, Gluconolactone, Retinol, Dextran, Trifluoroacetyl Tripeptide-2, Geraniol**, Citronellol**, Linalool**, Eugenol**, Limonene**, Citral**, Farnesol**, Benzyl Benzoate**, Benzyl Salicylate**, Isoeugenol**.

*Denotes organically produced ingredient. **Denotes component of essential oils.